Table 4.
Maternal and fetal Doppler velocimetry, and main obstetric outcomes among controls and subjects with undifferentiated connective tissue disease (UCTD), major rheumatic diseases and no criteria for diagnosis
| Controls n = 597 | UCTD n = 131 | Major rheumatic diseases n = 68 | No criteria for diagnosis n = 150 | p | |
|---|---|---|---|---|---|
| mean (SD) | mean (SD) | mean (SD) | mean (SD) | ||
| I st trimester Uterine artery PI | 1.16 (0.3) | 1.64 (0.3) | 1.80 (0.4) | 1.37 (0.4) | <.001 |
| II nd trimester Uterine artery PI | 0.87 (0.4) | 1.29 (0.2) | 1.33 (0.3) | 1.00 (0.3) | <.001 |
| III rd trimester Umbilical Artery PI | 0.89 (0.1) | 0.95 (0.2) | 1.03 (0.3) | 0.95 (0.20) | <.001 |
| N (%) | N (%) | N (%) | N (%) | ||
| Uterine artery bilateral notch | |||||
| Ist trimester | 23 (3.8) | 33 (25.2) | 30 (44.1) | 14 (9.3) | <.001 |
| IInd trimester | 14 (2.3) | 15 (11.5) | 18 (26.5) | 9 (6) | <.001 |
| Umbilical artery PI >95° percentile | 25 (4.2) | 21 (16) | 18 (26.5) | 24 (16) | <.001 |
| Miscarriage | 2 (0.3) | 1 (0.6) | 0.6 | ||
| Stillbirth | 1 (0.2) | 1 (1.5) | 0.3 | ||
| Gestational diabetes | 13 (2.2) | 4 (3.1) | 4 (5.8) | 6 (4.0) | 0.35 |
| Small for gestational age | 46 (7.7) | 23 (17.5) | 18 (26.5) | 17 (11.3) | <.001 |
| Fetal growth restriction (FGR) | 25 (4.2) | 21 (16) | 18 (26.5) | 20 (13.3) | <.001 |
| Preeclampsia | 19 (3.2) | 18 (13.7) | 15 (22.1) | 9 (6) | <.001 |
| Preclampsia or FGR | 36 (6) | 30 (22.9) | 20 (29.4) | 22 (14.6) | <.001 |
| Delivery less than 34 weeks | 17 (2.8) | 6 (4.6) | 5 (7.4) | 4 (2.6) | 0.2 |
| Cesarean section | 183 (30.6) | 58 (44.3) | 34 (50) | 46 (30.6) | 0.001 |
SD standard deviation, PI pulsatility index
p values obtained by one-way anova or chi-square test