Table 2.
Clinical characteristics of Patients before and 1 year after transition to insulin pump
| Characteristics | All Patients (N = 91) | Group 1 (N = 33) | Group 2 (N = 58) | P value |
|---|---|---|---|---|
| Pre-BMI z-score | 0.6 ± 0.9 | 1.01 ± 0.7 | 0.38 ± 0.85 | <0.001 |
| Post-BMI z-score | 0.80 ± 0.7 | 0.69 ± 0.8 | 0.85 ± 0.7 | <0.001 |
| Pre-Post BMI z-score | 0.79 ± 0.72 | -0.31 ± 0.23 | 0.47 ± 0.43 | <0.001 |
| Pre-TDD (U/kg) | 0.9 ± 0.2 | 0.8 ± 0.2 | 0.9 ± 0.2 | NS |
| Post- TDD (U/kg) | 0.9 ± 0.2 | 0.8 ± 0.2 | 0.9 ± 0.2 | NS |
| Pre % Basal | 43.9 ± 11.6 | 43.5 ± 12.8 | 44.3 ± 10.9 | NS |
| Post % Basal | 40.7 ± 9.2 | 36.9 ± 7.6 | 42.8 ± 9.3 | <0.05 |
| Pre-bolus:basal | 1.4 ± 0.7 | 1.5 ± 0.8 | 1.4 ± 0.7 | NS |
| Post-bolus:basal | 1.6 ± 0.7 | 1.8 ± 0.6 | 1.5 ± 0.63 | <0.05 |
| Pre- HbA1c | 8.1 ± 0.9 | 7.8 ± 0.9 | 8.3 ± 0.8 | <0.01 |
| Post- HbA1c | 7.7 ± 0.7a | 7.7 ± 0.7 | 7.7 ± 0.6a | NS |
| Pre-FBG | 182.3 ± 45.3 | 179.8 ± 39.9 | 183.2 ± 48.8 | NS |
| Post-FBG | 163.3 ± 32.4 | 162.5 ± 33.7 | 163.4 ± 31.7 | NS |
| Pre-hypo/2 week | 1.81 + 0.85 | 1.48 ± 0.75 | 1.99 ± 0.86 | <0.01 |
| Post-hypo/2 week | 1.35 + 0.85b | 1.0 ± 0.4a | 1.53 ± 0.9a | <0.01 |
| Pre-Activity Level | 2.0 + 0.66 | 2.0 + 0.63 | 2.0 + 0.68 | NS |
| Post-Activity Level | 2.2 + 0.69 | 2.2 + 0.60 | 2.2 + 0.74 | NS |
Data are mean ± SD. Total daily dose (TDD), fasting blood glucose (FBG). “Pre” values represent baseline data collected at the beginning of the study per group. “Post” values represent data collected after one year of insulin pump therapy
p value, comparison between Group 1 vs. Group 2
a p < 0.01, Comparison between pre and post characteristics
b p < 0.001, Comparison between pre and post characteristics