Table 1.
Inhibition ratios of mRNA levels and protein levels
| Particles | mRNA levels mean ± SD | protein levels mean ± SD (pg/ml) | ||||||
|---|---|---|---|---|---|---|---|---|
| Particle | Particle + TNF-LV | Particle + N.C-LV | IRa | Particle | Particle + TNF-LV | Particle + N.C-LV | IRa | |
| TI | 24.06 ± 5.06 | 11.26 ± 3.48 | 1.50 ± 0.57 | 53.22 % | 780.12 ± 36.36 | 490.03 ± 8.80 | 730.06 ± 45.88 | 37.18 % |
| CE | 9.01 ± 1.49 | 4.82 ± 0.22 | 1.50 ± 0.57 | 46.52 % | 572.11 ± 38.41 | 329.73 ± 17.22 | 527.11 ± 44.68 | 42.37 % |
aIR (Inhibition ratio) = (mRNA or protein levels of Group Particle minus Group Particle + TNF-LV)/Group Particle. There were no significant differences in RNAi inhibitory effects among titanium and ceramic particle stimulation groups in both mRNA levels and protein levels (P > 0.05)