Table 3.
Logistic regression analyses
| Dependent variable categorical outcome at month 6 | Independent variable score at baseline | p-value | Level/Unit | Odds Ratio | 95 % CI |
|---|---|---|---|---|---|
| Remission | |||||
| HAMD-17 | RDQ | 0.439 | Remission | 0.76 | 0.38, 1.52 |
| HAMD-17 | 0.009 | 1 unit | 0.81 | 0.70, 0.95 | |
| Relapse | |||||
| MINI | RDQ | 0.071 | 1 unit | 0.98 | 0.96, 1.00 |
| HAMD-17 | 0.007 | 1 unit | 1.21 | 1.05, 1.39 | |
| Composite remission status | |||||
| QIDS-SR + SDS + EQ-5D | RDQ | 0.553 | 1 unit | 0.99 | 0.96, 1.02 |
| HAMD-17 + SOFAS | RDQ | 0.374 | 1 unit | 0.99 | 0.97, 1.01 |
| Functioning | |||||
| HAMD-17 | SDS | 0.789 | No impairment | 1.09 | 0.57, 2.09 |
| HAMD-17 | 0.017 | 1 unit | 0.81 | 0.69, 0.96 | |
| HAMD-17 | SOFAS | 0.917 | Good functioning | 1.03 | 0.55, 1.95 |
| HAMD-17 | 0.024 | 1 unit | 0.83 | 0.71, 0.98 | |
| Healthcare resource utilizationa | |||||
| Healthcare resources | RDQ | 0.568 | Remission | 0.89 | 0.59, 1.33 |
Abbreviations: CI confidence interval, EQ-5D EuroQol, HAMD-17 17-item Hamilton Rating Scale for Depression, MINI mini-International neuropsychiatric interview, QIDS-SR quick inventory of depressive symptomatology-self report, RDQ remission from depression questionnaire, SDS Sheehan disability scale, SOFAS social and occupational functioning assessment scale
aHealthcare Resource Utilization was coded as a categorical outcome with at least one visit receiving a ‘Yes’