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. 2016 Sep;13(3):313–324. doi: 10.20892/j.issn.2095-3941.2016.0065

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Copyright 2016 Cancer Biology & Medicine

This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/

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(A) Schematic illustration of combined ultrasonic imaging and enhanced photothermal therapy with CuS-ST68 MBs through UTMD. (B) In vitro US contrast-enhanced images in a latex tube before and after CuS-ST68 MBs injection in PIHI contrast mode and B-mode. The CuS-ST68 MBs could be disrupted to lose imaging capability (red circled area) through UTMD upon enhanced US, showing the potential of targeted delivery of CuS NPs to tumor. (C) Concentration-dependent photothermal temperature elevation upon exposure to NIR light (808 nm, 2 W). (D) HeLa cell viability after treatment with different concentrations of CuS-ST68 MBs with or without NIR laser irradiation. Reproduced with permission from Ref. 63. Copyright 2013 Royal Society of Chemistry.