Table 2.
Clinical characteristics of patients with KPLA stratified by non-diabetic and diabetic with optimal glycemic control
| Non-DM (n = 120) |
DM with HbA1c < 7 % (n = 19) |
p | |
|---|---|---|---|
| Age in years | 64.1 ± 16.3 | 69.5 ± 12.9 | 0.166 |
| Male | 69 (57.5) | 13 (68.4) | 0.369 |
| Charlson score | 1.1 ± 1.8 | 2.0 ± 1.4 | 0.047 |
| Underlying disease | |||
| Malignancy | 11 (9.2) | 3 (15.8) | 0.408 |
| Alcoholism | 4 (3.3) | 0 (0) | 1.000 |
| Chronic kidney disease | 4 (3.3) | 3 (15.8) | 0.054 |
| Liver cirrhosis | 5 (4.2) | 0 (0) | 1.000 |
| Congestive heart failure | 8 (6.7) | 2 (10.5) | 0.627 |
| Chronic lung disease | 5 (4.2) | 1 (5.3) | 0.593 |
| Cerebrovascular accident | 11 (9.2) | 0 (0) | 0.361 |
| APACHE II score | 12.3 ± 6.9 | 14.9 ± 8.4 | 0.136 |
| Capsular type K1 and K2 | 94 (81.7)a | 12 (75.0)b | 0.506 |
| Wild-type antibiotic susceptibility | 113 (94.2) | 17 (89.5) | 0.355 |
| Origin | 1.000 | ||
| Cryptogenic | 103 (85.8) | 17 (89.5) | |
| Biliary tract origin | 17 (14.2) | 2 (10.5) | |
| Abscess location | 0.937 | ||
| Right lobe | 77 (64.2) | 12 (63.2) | |
| Left lobe | 21 (17.5) | 4 (21.1) | |
| Both lobes | 22 (18.3) | 3 (15.8) | |
| Abscess size | 0.369 | ||
| <5 cm | 51 (42.5) | 6 (31.6) | |
| ≥5 cm | 69 (57.5) | 13 (68.4) | |
| Gas-forming abscess | 2 (1.7) | 3 (15.8) | 0.018 |
| Multiple abscesses | 18 (15.0) | 3 (15.8) | 1.000 |
| Metastatic infection | 6 (5.0) | 1 (5.3) | 1.000 |
| Outcomes | |||
| ICU admission | 23 (19.2) | 3 (15.8) | 1.000 |
| Hospital days | 26.9 ± 16.5 | 28.1 ± 21.1 | 0.786 |
| Mortality | 4 (3.4) | 0 (0) | 1.000 |
Data are presented as mean ± SD or frequency with percentage (%)
a115 isolates were available for genotyping
b16 isolates were available for genotyping