Table 4.

Status of the target gene expression, diets and sex of offspring

Gene	Variable’s level		Ba	SE	p value	OR (95 % CI)
Runx2	Diets	LF-HCD	-	-	0.9	1
		HF-LCD	−40.6	1.3		0.001 (0.001, 0.001)
	Sex	Female	-	-	0.9	1
		Male	−18.4	9.1		0.001 (0.001, 0.001)
OPG	Diets	LF-HCD	-	-	<0.001*	1
		HF-LCD	−3.7	0.95		0.02 (0.004, 0.16)
	Sex	Female	-	-	0.19	1
		Male	1.2	0.89		3.2 (0.55, 18.3)
OPG/RANK-L	Diets	LF-HCD	-	-	0.12	1
		HF-LCD	−1.01	0.65		0.36 (0.1, 1.31)
	Sex	Female	-	-	0.02*	1
		Male	−1.6	0.7		0.2 (0.05, 0.78)
Ctnnb1	Diets	LF-HCD	-	-	<0.001*	1
		HF-LCD	−3.5	0.88		0.03 (0.005, 0.17)
	Sex	Female	-	-	0.6	1
		Male	0.44	0.82		1.5 (0.31, 7.73)
PPARɤ2	Diets	LF-HCD	-	-	0.004*	1
		HF-LCD	1.95	0.68		7.1 (1.83, 27.1)
	Sex	Female	-	-	0.13	1
		Male	1.04	0.69		2.8 (0.73, 11.1)
FASN	Diets	LF-HCD	-	-	0.99	1
		HF-LCD	21.9	817		0.001 (0.001, 0.001)
	Sex	Female	-	-	0.56	1
		Male	0.51	0.87		1.66 (0.3, 9.3)
AdipoQ	Diets	LF-HCD	-	-	<0.001*	1
		HF-LCD	2.8	0.74		15.8 (3.7, 67.4)
	Sex	Female	-	-	0.4	1
		Male	−0.62	0.74		0.53 (0.125, 2.3)
Lep	Diets	LF-HCD	-	-	0.99	1
		HF-LCD	40.1	102		0.001 (0.001, 0.001)
	Sex	Female	-	-	0.99	1
		Male	−19.7	72		0.001 (0.001, 0.001)
LPL	Diets	LF-HCD	-	-	0.03*	1
		HF-LCD	1.44	0.68		4.2 (1.1, 16.2)
	Sex	Female	-	-	0.87	1
		Male	0.11	0.66		1.1 (0.3, 4.1)

p values are calculated with the logistic regression model

LF-HCD low fat-high carbohydrate diet, HF-LCD high fat-low carbohydrate diet, OR odds ratio, CI confidence interval, OPG osteoprotegerin, RANK-L nuclear factor (NF-kB) ligand, PPRRɤ2 Peroxisome proliferator-activated receptor gamma 2, FASN fatty acid synthase, AdipoQ adiponectin, Lep leptin, LPL lipoprotein lipase

^aEstimated regression coefficients and corresponded standard errors of logistic regression model

^*significant differences adjusted for maternal diet and/or sex of offspring