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Snail knockdown results in an increased sensitivity to programmed cell death induced by ADR treatment. (a) A375 cells infected with shRNA-Snail or mock adenovirus were treated with ADR, and TUNEL-positive cells were detected by using immunofluorescence. (b) Quantitation of the TUNEL assays described in panel a. All data represent the mean value ± the standard deviation of three independent experiments. ✽, P < 0.05 (as determined by using the Student t test).
