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. 2016 May 17;6(5):e810. doi: 10.1038/tp.2016.80

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Copyright © 2016 Macmillan Publishers Limited

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Flow chart depicting the analyses performed in this study. (a) A meta-analysis was first conducted to identify a pVMPFC region implicated in mood and anxiety disorders. (b) Task-based and intrinsic connectivity related to anhedonia and general distress were then examined in both depressed patients and healthy controls. Confirmatory correlation and partial correlation analyses were used to confirm the robustness of the findings. FC, functional connectivity; gPPI, generalized form of psychophysiological interaction; ROI, region of interest.