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. 2016 May 10;6(5):e806. doi: 10.1038/tp.2016.66

Figure 2.

Figure 2

The effect of Fgf14 genetic ablation on GABAergic presynaptic proteins in the hippocampal CA1 region. (a, b) GAD67 representative puncta in CA1 stratum pyramidalis (SP) at high magnification. (c) Quantification of GAD67 puncta area, puncta intensity and puncta number in the indicated genotypes. (d, e) Vesicular GABA transporter (VGAT) representative puncta in CA1 SP at high magnification. (f) Quantification of VGAT puncta area, puncta intensity and puncta number in the indicated genotypes. (g) Quantitative western blot analysis of GAD67 and VGAT from the hippocampus. (h) Immunoblot detection of GAD67 and VGAT in whole hippocampal homogenates from Fgf14−/−mice and Fgf14+/+ controls. Data represent mean±s.e.m., ***P<0.001; **P<0.02; *P<0.05 statistical differences were assessed by Student's t-test or non-parametric Mann–Whitney test. Scale bars, 20 μm (a, d). GABA, gamma-amino-butyric acid; GAD67, glutamic acid decarboxylase 67.