FIG. 3.

Cyclin D1 heterozygosity reduces duodenal polyp number in Apc^Min mice. (A) In vivo BrdU staining of the duodenum (n = 9 animals), shown as mean and standard error of the mean/crypt, in Apc^Min mice by cyclin D1 genotype (13 weeks). (B to D) Mean numbers of polyps in Apc^Min/cyclin D1^wt and heterozygote mice (data are based on comparisons from nine mice [four cyclin D1^+/+ and five cyclin D1^+/−]) overall (B), in the duodenum (C), and in the jejunum-ileum (D). Asterisks indicate P values <0.05.