Table 1.
Demographic Information for Human Lung Explants, Primary PASMCs, and Plasma
| Sample Source | n Age Gender |
|---|---|
| IPAH lung tissue (n) | 9 |
| Age, yr | 38.3 (14-56) |
| Female | 4 (44.4) |
| PAH category | |
| Idiopathic PAH | 8 (88.9) |
| Heritable PAH (BMPR2 mutation) | 1 (11.1) |
| IPAH PASMCs (n) | 4 |
| Age, yr | 39.0 (26-52) |
| Female | 3 (75.0) |
| PAH category | |
| Idiopathic PAH | 3 (75.0) |
| Heritable PAH (BMPR2 mutation) | 1 (25.0) |
| PAH plasma (n) | 26 |
| Age, yr | 48.5 (28-76) |
| Female | 19 (73.0) |
| PAH category | |
| Idiopathic PAH | 12 (46.0) |
| Associated PAH | 14 (54.0) |
| Control lung tissue (n) | 9 |
| Age, yr | 42.8 (17-64) |
| Female | 2 (22.2) |
| Control PASMCs (n) | 4 |
| Age, yr | 47.3 (42-57) |
| Female | 3 (75.0) |
| Control plasma (n) | 12 |
| Age, yr | 31.3 (18-55) |
| Female | 8 (67.0) |
Definition of abbreviations: BMPR2, bone morphogenic protein type 2 receptor; IPAH, idiopathic pulmonary arterial hypertension; PAH, pulmonary arterial hypertension; PASMCS, pulmonary arterial smooth muscle cells.
Data are presented as mean (range: MIN–MAX) or No. (%) as appropriate.