Table 5.
Pathway enrichment analysis of the selected 34 genes constituting the simplified prediction model
| Cluster Profiler pathway enrichment analysis | ||||
| KEGG ID | Description | Adjusted p-value |
FDR q-value |
Gene IDs |
| hsa03030 | DNA replication | 2.07E-02 | 7.28E-03 | POLE/MCM5 |
| hsa04974 | Protein digestion and absorption | 3.09E-02 | 1.08E-02 | PRSS1/PRSS2 |
| hsa03010 | Ribosome | 3.09E-02 | 1.08E-02 | RPS23/RPS20 |
| hsa00240 | Pyrimidine metabolism | 3.09E-02 | 1.08E-02 | POLE/ENTPD5 |
| hsa04972 | Pancreatic secretion | 3.09E-02 | 1.08E-02 | PRSS1/PRSS2 |
| GeneGO pathway enrichment analysis | ||||
| # | Description | Adjusted p-value |
FDR q-value |
Gene IDs |
| 1 | Cell adhesion_Chemokines and adhesion | 8.45E-03 | 9.91E-02 | Thrombospondin 1, TRIO |
| 2 | Immune response_IL-12 signaling pathway | 3.21E-02 | 9.91E-02 | G6NT |
| 3 | Cytoskeleton remodeling_Role of PDGFs in cell migration | 3.34E-02 | 9.91E-02 | PDGF-D |
| 4 | Triacylglycerol metabolism p.2 | 3.89E-02 | 9.91E-02 | CEL |
| 5 | Development_Thrombospondin-1 signaling | 3.89E-02 | 9.91E-02 | Thrombospondin 1 |
| 6 | Cell cycle_Start of DNA replication in early S phase | 4.43E-02 | 9.91E-02 | MCM5 |
| 7 | Role of Tissue factor in cancer independent of coagulation protease signaling | 4.84E-02 | 9.91E-02 | Thrombospondin 1 |