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. 2016 Oct 19;17:812. doi: 10.1186/s12864-016-3147-7

Table 6.

Overrepresented gene ontology terms for moderate impactb, line-specific variants in Fayoumi and Leghorn lines

Fayoumi GO Term Count P-valuea
FN3 22 1.10E-03
Ribonucleotide binding 154 1.70E-03
Purine ribonucleotide binding 154 1.70E-03
Fibronectin, type III 22 8.10E-03
PTPc 8 1.70E-02
Nucleotide binding 177 2.10E-02
Protein kinase activity 61 2.60E-02
Leghorn GO Term Count P-valuea
ECM-receptor interaction 25 9.60E-05
Extracellular matrix 41 1.90E-04
Metal ion binding 270 2.30E-03
Proteinaceous extracellular matrix 37 1.30E-03
Extracellular region 94 2.30E-03
Cell division and chromosome partitioning 26 2.60E-02
Calcium ion binding 77 3.90E-02
Aminophospholipid transporter activity 7 4.30E-02
Phospholipid-translocating atpase activity 7 4.30E-02

Over-represented GO terms for moderate impact variants (fixed/segregating) and unique for the inbred Fayoumi and Leghorn lines. aBenjamini-Hochberg Corrected p-value cut-off α = 0.05. bModerate impact variants: non_synonymous_coding, codon_change, codon_insertion, codon_change_plus_codon_insertion, codon_deletion, codon_change_plus_codon_deletion, utr_5_deleted, utr_3_deleted