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. 2016 Oct 18;9:111. doi: 10.1186/s13045-016-0340-8

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Forest plot and pooled HR and 95% CI for subgroup OS: anti-angiogenesis therapy versus non-anti-angiogenesis therapy. HR hazard ratios, CI confidence intervals, OS overall survival. (a: OS of subgroups of angiogenesis inhibitors alone threapy; b: OS of subgroups of angiogenesis inhibitors combined with chemotherapy threapy; c: OS of subgroups of the first line threapy; d: OS of subgroups of the second line threapy; e: OS of subgroups of anti-VEGF threapy; f: OS of subgroups of anti-VEGFR and multiple receptor inhibitors threapy)