Fig. 5.

Activation of NF-κB target genes in MSCs by ATL-derived exosomes. a, b Histograms representing the normalized fold expression of α-SMA, N-cadherin, CXCR4 and MMP-9 in MSCs control or co-cultured with HuT-102-derived exosomes, as detected by qPCR (*p < 0.05; ***p < 0.005). c Representative western blots of VEGF expression in MSCs control or co-cultured with Molt-4, C81 and HuT-102-derived exosomes. Actin was used as an internal loading control. d Histogram representing the densitometry analysis of VEGF protein expression from two independent western blot experiments