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. 2016 May 23;1(3):e000052. doi: 10.1136/esmoopen-2016-000052

Table 3.

Univariate analysis for relapse-free survival (Cox proportional hazards regression model)

Factors HR 95% CI p Value
Age (<61/≥62 years) 1.125 0.677 to 1.854 0.645
Sex (male/female) 1.073 0.641 to 1.772 0.786
Primary colorectal tumour (rectum/others) 1.237 0.704 to 2.094 0.448
CEA level (≥40/≤40) 1.824 1.054 to 3.042 0.032
Tumour invasion (T4a–b/T3) 1.229 0.728 to 2.035 0.433
Lymph node metastasis (N2/N0–1) 1.753 1.051 to 2.892 0.032
Lymphatic invasion (present/absent) 0.718 0.371 to 1.564 0.380
Venous invasion (present/absent) 1.025 0.452 to 2.943 0.958
Synchronous metastasis (both/lung)
(liver/lung)
4.332
2.010
1.284 to 13.148
1.049 to 4.353
0.020
0.034

Underlined values indicate p values of <0.1.

Rectum includes upper and lower rectum and anal canal.

Both: synchronous liver and lung metastases.

CEA, carcinoembryonic antigen.