Table 2.
Effects (mean ± SEM) of scopolamine rats in the light–dark transition model (n = 20 animals/group)
| Time spent (s) | Total distance moved (cm) | Number of transitions | |||
|---|---|---|---|---|---|
| Light | Dark | Light | Dark | ||
| Normal | 140 ± 8.5 | 520 ± 7.45 | 1400 ± 304 | 2400 ± 235 | 9.7 ± 0.45 |
| Saline | 140 ± 7 | 528 ± 7.45 | 1350 ± 132 | 2340 ± 234 | 10.05 ± 0.75 |
| Scopolamine treatment (mg/Kg) | |||||
| 0.3 | 275.7 ± 10. | 190 ± 8.5 | 1269 ± 200 | 2154 ± 159 | 9.2 ± 1.2 |
| 0.9 | 283 ± 3.5 | 182 ± 8.5 | 2000 ± 304 | 1564 ± 144 | 9.55 ± 0.5 |
| 1.2 | 350.9 ± 15 | 1790 ± 7 | 2150 ± 132 | 1812 ± 128 | 9.5 ± 1.5 |
| 1.8 | 409 ± 6.3 | 183 ± 10.32 | 2252 ± 150 | 1765 ± 235 | 9.01 ± 0.6 |