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. 2016 Oct 19;16:811. doi: 10.1186/s12885-016-2848-2

Table 5.

Association of the BRCA1-like profile with clinical parameters

Variable Valid cases MLPA data p-value
(n) BRCA1-like Non-BRCA1-like
Total 144 63 81
Age 143 0.265
 <50 54 27 27
 ≥50 89 36 53
Tumor size 143 0.979
 pT 1 54 24 30
 pT 2 69 31 38
 pT 3 8 3 5
 pT 4 12 5 7
Nodal status 141 0.145
 Negative 71 35 36
 Positive 70 26 44
Histological grade 139 0.0004*
 1 6 0 6
 2 28 5 23
 3 105 57 48
Histology 144 0.062
 Invasive-ductal 113 53 60
 Invasive-medullary 11 6 5
 Other 20 4 16
Adjuvant chemotherapy 142 0.044*
 None 34 10 24
 Yes 108 53 55
Radiation therapy 142 0.017*
 None 23 5 18
 Yes 119 58 61

BRCA1-like classification with cut-off value ≥ 0.5, non-BRCA1-like classification with cut-off value < 0.5

*statistically significant with chi square test