Table 5.
Variable | Valid cases | MLPA data | p-value | |
---|---|---|---|---|
(n) | BRCA1-like | Non-BRCA1-like | ||
Total | 144 | 63 | 81 | |
Age | 143 | 0.265 | ||
<50 | 54 | 27 | 27 | |
≥50 | 89 | 36 | 53 | |
Tumor size | 143 | 0.979 | ||
pT 1 | 54 | 24 | 30 | |
pT 2 | 69 | 31 | 38 | |
pT 3 | 8 | 3 | 5 | |
pT 4 | 12 | 5 | 7 | |
Nodal status | 141 | 0.145 | ||
Negative | 71 | 35 | 36 | |
Positive | 70 | 26 | 44 | |
Histological grade | 139 | 0.0004* | ||
1 | 6 | 0 | 6 | |
2 | 28 | 5 | 23 | |
3 | 105 | 57 | 48 | |
Histology | 144 | 0.062 | ||
Invasive-ductal | 113 | 53 | 60 | |
Invasive-medullary | 11 | 6 | 5 | |
Other | 20 | 4 | 16 | |
Adjuvant chemotherapy | 142 | 0.044* | ||
None | 34 | 10 | 24 | |
Yes | 108 | 53 | 55 | |
Radiation therapy | 142 | 0.017* | ||
None | 23 | 5 | 18 | |
Yes | 119 | 58 | 61 |
BRCA1-like classification with cut-off value ≥ 0.5, non-BRCA1-like classification with cut-off value < 0.5
*statistically significant with chi square test