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. Author manuscript; available in PMC: 2017 Jan 11.
Published in final edited form as: Biomacromolecules. 2015 Dec 11;17(1):154–164. doi: 10.1021/acs.biomac.5b01280

Figure 4.

Figure 4

Effect of RNA interaction on the dendrimer. 1H NMR spectra of 5 μM G5-PEG titrated with increasing concentrations of TAR to decreasing N:P ratios with assignments of 1H NMR peaks of G5-PEG mapped onto its chemical structure shown above the NMR spectra. Peak assignments are based on previously published studies.12,31 Peaks representing PAMAM framework of G5-PEG are broadened while PEG peaks remain sharp suggesting that the RNA is binding to the PAMAM part while the PEG arms remain flexible.