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. 2016 Sep 15;75(11):1058–1071. doi: 10.1093/jnen/nlw081

FIGURE 1.

FIGURE 1

IL-4 skews the infarcted striatum toward an anti-inflammatory phenotype. Rats were injected with saline (sham control, black bars), ET-1 (ischemic control; white bars) or ET-1 + 500 ng of rat recombinant IL-4 (ET-1 + IL-4; gray bars). Transcript levels of pro-inflammatory (A), anti-inflammatory (B) and other immunomodulatory molecules (C) were quantified in the ipsilateral striatum at 1, 3, and 7 days. The symbols represent: * differences from saline-injected shams; † time-dependent changes within a treatment group; # IL-4 effects. One symbol indicates p < 0.05; 2 symbols, p < 0.01; 3 symbols, p < 0.001.