Table 3.
Summary of Study Characteristics Included in Meta-analysis15
| Characteristics | No. of Studies* | Median value or proportion across studies | Range of values or proportions across studies |
|---|---|---|---|
| Age, Years | 20 | 53.7 | 43.0–62.1 |
| Type of IBTR | |||
| DCIS | 17 | 50.0% | 0.0–75.0% |
| Invasive | 17 | 50.0% | 25.0–100.0% |
| Unknown | 17 | 0.0% | 0.0–7.1% |
| Screen Detected | |||
| Yes | 14 | 85.8% | 45.6–100.0% |
| No | 14 | 14.2% | 0.0–54.4% |
| Unknown | 14 | 0.0% | 0.0–2.8% |
| Grade | |||
| I | 13 | 17.5% | 1.8–64.5% |
| II | 13 | 28.0% | 5.5–45.0% |
| I–II | 16 | 57.3% | 7.3–92.5% |
| III | 16 | 28.4% | 3.5–45.6% |
| Unknown | 16 | 9.2% | 0.0–87.3% |
| Hormone Receptor | |||
| Positive | 5 | 50.4% | 23.0–80.4% |
| Negative | 5 | 8.7% | 2.8–14.3% |
| Unknown | 5 | 40.9% | 14.8–69.8% |
| WBRT Dose (Gy median) | 11 | 50.0 | 42.5–50.0 |
| Radiation Boost | 19 | 70.9% | 0.0–100% |
| Boost Dose (Gy median) | 8 | 10.0 | 10.0–10.8 |
IBTR, ipsilateral breast tumor recurrence; DCIS, ductal carcinoma in situ; WBRT, whole breast radiation therapy
*
Number of studies refers to studies contributing information on the characteristic including studies with subsets of patients missing data for the characteristic.
Data from Marinovich ML, Azizi L, Macaskill P, et al. The Association of Surgical Margins and Local Recurrence in Women with Ductal Carcinoma In Situ Treated with Breast-Conserving Therapy: A Meta-Analysis. Ann Surg Oncol 2016 (In Press)