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Characterization of Fungizone® and mAmB.
| Formulation | Fungizone® | mAmB |
|---|---|---|
| Excipient:AmB ratio (mol/mol) |
2:1 | 2:1 |
| Final level of AmB (mg/mL) |
0.1 | 0.53 ± 0.04 |
| z-average particle diameter (nm) |
41.0 ± 0.4 | 70.4 ± 0.2 |
| Polydispersity index (PDI) |
0.393 ± 0.029 | 0.132 ± 0.017 |
| Peak ratio at 340 and 412 nm (I340/I412) |
3.80 ± 0.56 | 0.267 ± 0.013 |
