Fig. 3. Relationship between CA and NF-kB signaling in acute inflammation. BMDMs were isolated from mice and exposed to LPS (200 ng/mL) and/or CA (6 μM), Bay11-7082 (10 μM), or an IRAK inhibitor (2.5 μM) for 30 min. qPCR was used to measure mRNA levels of NLRP3 (A), IRAK1 (B), IRAK2 (C), and IRAK4 (D). *P ＜ 0.05, **P ＜ 0.01 versus the relevant control group.
