Table 4. Differentially expressed miRNAs with inflammatory and immunological functions in other species.
| DE miRNA | Species | Tissue | Disease | Expression | Target | Target function | Reference |
|---|---|---|---|---|---|---|---|
| mir-19b | Mouse | mir-17-92 deficient CD4+ T cells | \ | Decreased | PTEN | Inhibition of PI3K-AKT-mTOR | [103] |
| Mouse | mir-17-92 deficient Th1 cells | \ | Decreased | PTEN | Inhibition of PI3K-AKT pathway | [104] | |
| Pig | PK15 cell line | PPV infection | Decreased | DPP8 | Regulation of parvovirus immune response associated pathway | [105] | |
| Human | Serum | Tuberculosis | Decreased | n.d. | n.d. | [65] | |
| Human | Mucosal tissue | Crohn's disease | Decreased | n.d. | n.d. | [66] | |
| mir-19b-2 | Human | Sputum | Tuberculosis | Decreased | n.d. | Unknown | [62] |
| mir-100 | Mouse | Lungs | Viral infection | Increased | n.d. | n.d. | [38] |
| Shrimp | Hemocytes | Gram- infection | Increased | n.d. | n.d. | [60] | |
| Cow | Mammary epithelial cells | S. uberis infection | Decreased | n.d. | n.d. | [40] | |
| mir-301a | Mouse | Lung | Viral infection | Decreased | n.d. | n.d. | [38] |
| Mouse | TLR-triggered macrophages | \ | Decreased | NKRF | Inhibition of NF-kB | [106] | |
| mir-32 | Cow | Alveolar macrophages | Bovine tuberculosis | Increased | n.d. | n.d. | [63] |
| Human | CD4+ T cells | Tuberculosis | Decreased | n.d. | [61] | ||
| mir-24-2 | Human | PBMC | Tuberculosis | Increased | n.d. | [67] | |
| mir-378 | Human | Serum | Tuberculosis | Increased | MAPA1 | n.d. | [67] |
| Human | Platelets | Ulcerative colitis | Increased | n.d. | n.d. | [68] | |
| mir-1271 | Human | Platelets | Ulcerative colitis | Increased | n.d. | n.d. | [68] |