. Author manuscript; available in PMC: 2017 Nov 1.

Published in final edited form as: Arch Gynecol Obstet. 2016 Jul 11;294(5):991–997. doi: 10.1007/s00404-016-4143-5

Table 6.2.

Unadjusted and adjusted Odds Ratios of Heart Disease and Stroke by OC status: Using Combined Oral Contraceptives (COCs) as the Referent Group

	Heart Disease OR (95% CI)		Stroke OR (95% CI)

	Unadjusted (n=1219±)	Adjusted^£ (n=1197^±)	Unadjusted (n=177^±)	Adjusted^£ (n=175^±)
COC	1.00		1.00
Never User
EA	0.62 (0.42, 0.91)^*	0.64 (0.44, 0.96)^*	0.44 (0.14, 1.40)	0.46 (0.14, 1.46)
AA	0.89 (0.81, 0.98)^*	0.65 (0.49, 0.87)^*	1.13 (0.64, 1.99)	1.28 (0.72, 2.27)
Total	0.63 (0.51, 0.79)^*	0.65 (0.52, 0.82)^*	0.88 (0.53, 1.46)	0.95 (0.57, 1.59)
POC
EA	0.95 (0.63, 1.43)	0.74 (0.49, 1.12)	0.25 (0.04, 1.80)	0.19 (0.03, 1.38)^¥
AA	1.13 (0.82, 1.58)	0.75 (0.53, 1.05)^¥	0.81 (0.30, 2.22)	0.55 (0.20, 1.50)
Total	1.06 (0.82, 1.37)	0.74 (0.57, 0.97)^*	0.56 (0.23, 1.37)	0.39 (0.16, 0.95)^*
POC+ COC
EA	1.91 (1.46, 2.48)^*	2.07 (1.58, 2.72)^*	1.63 (0.81, 3.29)	1.98 (0.97, 4.05)^¥
AA	2.36 (1.91, 2.91)^*	2.42 (1.94, 3.01)^*	1.93 (1.07, 3.48)^*	2.21 (1.22, 4.01)^*
Total	2.16 (1.83, 2.55)^*	2.28 (1.92, 2.70)^*	1.80 (1.14, 2.82)^*	2.12 (1.34, 3.35)^*

Referent group: COC (Combined oral contraceptive); POC (Progestin-only oral contraceptive); POC+COC (Combined progestin-only method and combined oral contraceptive method); Each oral contraceptive group is mutually exclusive; EA (European American); AA (African American); Total (All Races)

^£

Adjusted for age, years, duration of use, marital status, and education

^±

total

Significant (p <0.05)

^¥

Borderline significant (p < 0.10)