Table 2. Multivariable logistic analyses for serum miR-21 and miR-92a levels and various diagnostic factors in patients with adenoma.

Variables	OR (% CI *)	p-Value
Adenoma patients vs control subjects
Age, >66 y vs ≤66 y†	0.61 (0.21–1.75)	0.36
Sex, male vs female	1.14 (0.39–3.26)	0.80
miR-21 in serum, > 0.0484 vs ≤0.0484‡	5.24 (1.79–15.32)	0.0025
Adenoma patients vs control subjects
Age, >66 y vs ≤66 y†	0.88 (0.30–2.53)	0.81
Sex, male vs female	0.79 (0.25–2.40)	0.67
miR-29a in serum, >0.0088 vs ≤0.0088‡	5.27 (1.68–16.54)	0.0043
Adenoma patients vs control subjects
Age, >66 y vs ≤66 y†	0.73 (0.25–2.10)	0.56
Sex, male vs female	1.14 (0.39–3.31)	0.80
miR-92a in serum, >0.398 vs ≤0.398‡	5.94 (2.05–17.21)	0.001

CI * = confidence interval; OR = odds ratio.

^† Median age was 66 years respectively.

^‡ The cutoff values of serum miR-21, miR-29a and miR-92a in adenoma patients vs. control subjects were derived by receiver operating characteristic curves with Youden’s index.