Video 3. Additional signs and associated features of spasticity and disordered sensorimotor movements (Supplementary to Figure 1 and Experimental Procedures).
The behaviours shown in this video were not scored as part of the forelimb scale, but were frequently observed. Rats with bilateral pyramidotomy displayed prolonged forelimb muscle contractions and repeated muscle jerks when rearing. Furthermore, stepping with hindlimbs is abnormally high during swing phases (likely to due to increased activation of iliopsoas and other hip flexors) and the hindlimb heels are frequently incompletely placed down. Rats have tail twitches and are unstable during rearing.