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. 2016 Oct 20;1(17):e89829. doi: 10.1172/jci.insight.89829

Figure 2. Immune infiltration and molecular smoking signatures.

Figure 2

(A) T cell infiltration score (TIS), immune cell infiltration score (IIS), and IFN-γ expression scores correlated with the Wellcome Trust Sanger Institute (WTSI) Mutational Smoking Signature Framework in HPV-positive (green) and -negative (blue) tumors. (B) Correlation between nonsynonymous tumor mutational burden and smoking signature quantified by the WTSI Mutational Smoking Signature Framework in HPV-positive (green) and -negative (blue) tumors. All r values represent Pearson correlation coefficients. Two-tailed P values are presented for significance (<0.05). n = 280.