Skip to main content
. Author manuscript; available in PMC: 2017 Jul 24.
Published in final edited form as: Pharmacogenomics J. 2016 Apr 19;17(4):366–371. doi: 10.1038/tpj.2016.29

Table 2.

Genetic variants in ADRA1B associated with sensitivity to phenylephrine (ED50)

SNP Caucasians African-Americans
ED50, ng/min, geometric mean
(95% CI)		 ED50, ng/min, geometric mean
(95% CI)		 P-value*
Number of variant alleles Number of variant alleles
0 1 2 0 1 2
rs10070745 325
(234–452)
n=64		 n=0 n=0 208
(130–334)
n=27		 144
(69–299)
n=14		 n=0 0.015
*

P value adjusted for sex, BMI and Baseline Norepinephrine