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. Author manuscript; available in PMC: 2017 Jul 24.
Published in final edited form as: Pharmacogenomics J. 2016 Apr 19;17(4):366–371. doi: 10.1038/tpj.2016.29

Table 3.

Genetic variants of ADRA1B associated with maximum response to phenylephrine (Emax).

SNP Caucasians African Americans All
Emax, %
Median (IQR)		 P-value Emax, %,
Median (IQR)		 P-value P-value
Number of variant alleles Number of variant alleles
0 1 2 0 1 2
rs952037 82
(66 – 93)
n= 29		 85
(75 – 97)
n=31		 92
(72 – 100)
n=4		 0.39 87
(73 – 96)
n=11		 90
(82–98)
n=19		 94
(87–100)
n=11		 0.24 0.041
rs7737796 92
(82–98)
n=24		 79
(64–88)
n=32		 82
(66–99)
n =8		 0.053 95
(86–98)
n=10		 86
(76–94)
n=24		 98
(87–100)
n=7		 0.10 0.018
rs17057303 85
(75 – 96)
n=63		 61

n=1		 n=0 0.20 92
(82 – 99)
n=34		 85
(64 – 89)
n=7		 n=0 0.044 0.11