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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Pediatr Infect Dis J. 2016 Nov;35(11):1204–1210. doi: 10.1097/INF.0000000000001268

Table 1.

Clinical Characteristics*

N=12

Age (days) 59 (0.0, 574)

Gestational age (weeks) 39 (27, 39)

Weight (kg) 3.7 (2.9, 9.6)

Birth weight (kg) 3 (2.4, 4.3)

Male, n (%) 5 (42)

Race, n (%)
White 6 (50)
African American 6 (50)

Diagnosis, n (%)
Cardiomyopathy 4 (34)
Pulmonary hypertension 3 (25)
Congenital heart disease 3 (25)
Congenital diaphragmatic hernia 1 (8)
Respiratory failure 1 (8)

Serum creatinine (mg/dL) 0.5 (0.2, 1.6)

ECMO support, n (%)
Veno-arterial 11 (92)
Veno-venous 1 (8)

ECMO circuit configuration, n (%)
S3 8 (67)
Cardiohelp 4 (33)

Micafungin indication n (%)
Prophylaxis 11 (92)
Therapy 1 (8)

Micafungin dosing (mg/kg/day) 4 (4, 8)

Duration of therapy (days) 4 (2, 8)

Duration of ECMO support at time of
first micafungin dosing (days)
4 (2, 10)

Number of PK samples per infant 11 (6, 14)

PK samples obtained around, n (%)
Dose 1-2 12 (100)
Dose 4-5 6 (50)
*

Results are expressed as median (range) unless otherwise specified

Median serum creatinine for each subject over the study period.