Table 1.
Effect of CX3CR1 deficiency and STZ-diabetes on body weight and glycated hemoglobin.
Veh WT (7) | Veh KO (7) | STZ WT (12) | STZ KO (11) | |
---|---|---|---|---|
Body weight (g) | 32.2 ± 2.1 | 30.5 ± 1.7 | 22.9 ± 5.2* | 21.05 ± 4.8* |
Glycated hemoglobin (%) | 4.6 ± 0.2 | 4.9 ± 0.6 | 8.6 ± 1.6* | 9.4 ± 2.2* |
Glycated hemoglobin (mmol/mol) | 27 ± < 9 | 30 ± < 9 | 70 ± < 9* | 79 ± < 9* |
Veh, non diabetic mice; STZ, streptozotocin- induced diabetic mice; WT, CX3CR1 homozygous wild type; KO, CX3CR1 homozygous knockout. Data represent mean ± SD. N=7–12 mice. Asterisks indicate statistical significance, p<0.015 compared to respective veh group.