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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Osteoarthritis Cartilage. 2016 Jun 27;24(11):1989–1998. doi: 10.1016/j.joca.2016.06.014

Figure 2.

Figure 2

LIPUS protects against IL-1 ation of out IL-1 culture with and without IL-1 tal depletion of GAG content in human cartilage explants (n=3). LIPUS increased GAG content and rescued the IL-1d induced depletion of GAG from the cartilage matrix. B) Chondrocyte micromass cultures show disoriented and patchy GAG content in the presence of IL-1β, LIPUS protects GAG content in the presence of IL-1β and shows an apparent increase in GAG secretion in LIPUS treated samples. C) IL-1 inontent and rescuednts shows increased release of GAG contents into culture media. LIPUS reduced GAG breakdown in cartilage explants and significantly reduced IL-1βts shows GAG depletion. * represents significant difference between Ctrl and IL-1AG contents insignificant difference between IL-1 and IL-1AG contents into, and † significant difference between Ctrl and LIPUS groups, p=0.028. Bars indicate group means and error bars show 95% confidence intervals.