Table 2.
Maternal characteristics and medication use among women with history of migraine headache, full sample and calibration sample
| MoBa Study | MIMEGA Study | |||
|---|---|---|---|---|
| Triptans In Pregnancy | No Triptans In Pregnancy | Triptans In Pregnancy | No Triptans In Pregnancy | |
|
| ||||
| N=375 | N=3,829 | N=46 | N=334 | |
| Age in years (Mean, SD) | 30.9(4.3) | 30.3(4.4) | 31.5(5.9) | 30.7(4.9) |
| BMI (kg/m2) | ||||
| <18.5 | 2.7 | 3.5 | -- | -- |
| 18.5-25 | 60.3 | 61.6 | -- | -- |
| >25 | 37.1 | 34.9 | -- | -- |
| Multiparous | 47.7 | 51.8 | 69.6 | 82.6 |
| Married or cohabitating | 95.5 | 97.2 | 93.5 | 95.2 |
| Mother Education | ||||
| Primary or secondary | 30.1 | 35.6 | 67.4 | 75.5 |
| University or higher | 69.9 | 64.4 | 32.6 | 24.6 |
| Smoking during pregnancy | 11.7 | 12.7 | 8.7 | 6.6 |
| Alcohol during pregnancy | 20.3 | 15.2 | 8.7 | 1.8 |
| Folate Supplementation | 60.8 | 58.8 | 89.1 | 86.5 |
| Medications Taken In Pregnancy | ||||
| Opioids | 12.8 | 4.8 | 23.9 | 9.3 |
| Acetaminophen | 76.0 | 65.0 | 78.3 | 65.3 |
| NSAIDs | 22.4 | 12.1 | 23.9 | 6.0 |
| Anticonvulsants | 0.3 | 0.3 | -- | -- |
| Antidepressants | 1.6 | 1.5 | -- | -- |
| Benzodiazepines | 1.6 | 0.5 | -- | -- |
| Medications Before Pregnancy | ||||
| Triptans | 84.0 | 19.7 | 97.8 | 61.7 |
| Opioids | 7.7 | 5.1 | 21.7 | 18.3 |
| Acetaminophen | 46.1 | 45.4 | 73.9 | 65.0 |
| NSAIDs | 21.9 | 23.8 | 60.9 | 58.1 |
| Anticonvulsants | 0.5 | 0.3 | -- | -- |
| Antidepressants | 5.1 | 3.9 | -- | -- |
| Benzodiazepines | 1.3 | 1.0 | -- | -- |
| Maternal Depression | 12.3 | 12.2 | 8.7 | 4.2 |
| Migraine Type | ||||
| With Aura | -- | -- | 37.0 | 42.8 |
| Without Aura | -- | -- | 43.5 | 31.7 |
| Other/Do not know | -- | -- | 19.6 | 25.5 |
| Migraine Severity Score (MIGSEV) (Mean, SD) | -- | -- | 12.0(2.6) | 9.1(4.7) |
| Beliefs About Medicines Questionnaire (BMQ): Necessity Subscale (Mean, SD) | -- | -- | 18.1(4.0) | 13.9(5.0) |
| Beliefs About Medicines Questionnaire (BMQ): Concern Subscale (Mean, SD) | -- | -- | 15.4(4.2) | 13.5(4.5) |
1
Values reported are column percents; age, Migraine Severity Score, and Beliefs About Medicines Questionnaire are reported as mean (standard deviation)