Figure 1.

Oral treatment with PXS‐4728A inhibits constitutive lung and peripheral SSAO enzymic activity. Mice were exposed daily to CS or normal air for 4 days. Prior to each exposure, mice were treated by oral gavage with PXS‐4728A (2, 6 or 20 mg⋅kg⁻¹). Lungs and inguinal fat were collected, and SSAO activity was measured using radiometric or fluorimetric enzymic assays respectively. Responses are represented as a percentage of activity relative to the normal, air‐exposed, group. Data represent the means ± SEM from six mice per group. *P < 0.05; significantly different as indicated; one‐way ANOVA with Tukey's test.