Table 1.
Effect of forskolin on hepatotoxicity indices and liver index in CCl4‐intoxicated rats
| Group | ALT (U·L−1) | AST (U·L−1) | TC (g·L−1) | TG (g·L−1) | Albumin (g·L−1) | Liver index (%) |
|---|---|---|---|---|---|---|
| Control | 9.1 ± 1.18b | 16.6 ± 2.84b | 0.50 ± 0.12b | 0.99 ± 0.10b | 42.1 ± 1.91b | 2.86 ± 0.25b |
| CCl4 | 38.7 ± 3.64a | 45.5 ± 2.95a | 1.08 ± 0.15a | 1.56 ± 0.20a | 31.6 ± 3.10a | 4.63 ± 0.55a |
| Forskolin + CCl4 | 22.5 ± 4.67a , b | 31.3 ± 5.87a , b | 0. 62 ± 0.13b | 0. 86 ± 0.19b | 39.1 ± 3.83b | 3.24 ± 0.18b |
| Forskolin | 11.4 ± 2.55b | 18.4 ± 4.74b | 0. 46 ± 0.12b | 0. 95 ± 0.18b | 39.2 ± 2.63b | 3.23 ± 0.39b |
Data presented are means ± SD (n = 8).
a
P <0.05; significantly different from control group;
b
P <0.05; significantly different from CCl4 group; ANOVA followed by Tukey–Kramer post hoc test.