Figure 5.

Experiment 3: The effect of the CB₁ receptor antagonists (AM251 1 mg kg⁻¹ and rimonabant 10 mg kg⁻¹; both i.p.) treatment upon harmaline (30 mg kg⁻¹; i.p.) induced symptoms. (A) Tremor score, (B) rearing events per session and (C) grooming events per session. Results from the same treatment in the open field test are shown as (D) total distance moved (cm), (E) mobility duration (s) and (F) movement speed (cm s⁻¹). Data describing mobility duration and movement speed exhibited a normal distribution and are represented as mean ± SEM. Data describing tremor score, rearing events, grooming events and total distance moved were not normally distributed and are represented as medians with interquartile ranges as a box and maxima/minima as whiskers. * P < 0.05, significantly different from the harmaline only group. Numbers in parentheses indicate group sizes. 3/172 data points were detected as outliers and excluded from the presented analyses.