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. 2016 Mar 30;30(7):1148–1158. doi: 10.1111/jdv.13611

Table 2.

Summary of new starts for first‐ through seventh‐lines of therapy included in the current analyses; patients with psoriasis initiating new therapy during the registry

Ustekinumab Infliximab Adalimumab Etanercept Total
New therapy starts, N 1833 327 1303 537 4000
First‐line therapya 361 (19.7) 63 (19.3) 402 (30.9) 289 (53.8) 1115
Second‐line therapy 566 (30.9) 93 (28.4) 622 (47.7) 155 (28.9) 1436
Third‐line therapy 551 (30.1) 103 (31.5) 197 (15.1) 71 (13.2) 922
Fourth‐line therapy 248 (13.5) 49 (15.0) 71 (5.4) 16 (3.0) 384
Fifth‐line therapy 84 (4.6) 14 (4.3) 9 (0.7) 6 (1.1) 113
Sixth‐line therapy 21 (1.1) 5 (1.5) 2 (0.2) 0 28
Seventh‐line therapy 2 (0.1) 0 0 0 2

Data are presented as number of patients (%).

a

For lines of therapy beyond first‐line, the prior biologic may have been any of the four biologics included in these analyses or other biologics not approved for psoriasis (golimumab), those no longer available for treating psoriasis (efalizumab and alefacept) or those received via participation in a clinical study but not available for treatment of psoriasis (briakinumab).