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. 2016 Mar 31;3(3):177–188. doi: 10.1002/ehf2.12088

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© 2016 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Patient characteristics and clinical outcomes in patients classified by left ventricular ejection fraction. (A) 5‐day total urine volume. (B) 5‐day total fluid balance. (C) Serum creatinine values from baseline to intensive treatment end. (D) WRF incidence during intensive treatment. (E) blood urea nitrogen values from baseline to intensive treatment end. (F) Systolic BP at baseline and day 1. (G) Change in systolic BP between baseline and day 1. (H–K) Change between baseline and intensive treatment end in CVP (H), BNP (I), PAC (J), and PRA (K). *P < 0.05. BNP indicates brain natriuretic peptide; BP, blood pressure; BUN, blood urea nitrogen; CVP, central venous pressure; HFp(r)EF, heart failure patient with preserved (reduced) ejection fraction; TLV, tolvaptan; WRF, worsening renal function.