Table 1.
Baseline characteristics of the subjects in the full analysis set
| URSA‐S (n = 84) | Placebo (n = 81) | |
|---|---|---|
| Sex | ||
| Men | 68 (80.95) | 70 (86.42)* |
| Women | 16 (19.05) | 11 (13.58) |
| Age (years) | ||
| Average | 43.63 ± 11.79 | 43.72 ± 10.36† |
| < 30 | 5 (5.95) | 6 (7.41)* |
| 30–39 | 35 (41.67) | 29 (35.80) |
| 40–49 | 17 (20.24) | 22 (27.16) |
| > 50 | 27 (32.14) | 24 (29.63) |
| BMI (kg/m2) | 26.12 ± 2.56 | 26.27 ± 2.37† |
| Smoking | ||
| Non | 52 (61.90) | 48 (59.26)* |
| Ex | 15 (17.86) | 13 (16.05) |
| Current | 17 (20.24) | 20 (24.69) |
| Alcohol consumption | ||
| No | 71 (84.52) | 71 (87.65)* |
| Yes | 13 (15.48) | 10 (12.35) |
| Caffeine consumption | ||
| No | 6 (7.14) | 4 (4.94)‡ |
| Yes | 78 (92.86) | 77 (95.06) |
| HADS score | ||
| Anxiety | 5.58 ± 2.80 | 5.46 ± 2.80† |
| Depression | 6.67 ± 2.45 | 6.41 ± 2.70† |
| Total | 12.25 ± 4.58 | 11.86 ± 4.94† |
| CIS score | 89.81 ± 11.80 | 91.75 ± 12.10 |
| Liver function test | ||
| ALT (SGPT) | 47.58 ± 34.64 | 48.90 ± 27.08 |
| AST (SGOT) | 32.33 ± 16.27 | 32.47 ± 11.72 |
| γ‐GTP | 51.33 ± 40.74 | 58.54 ± 50.22 |
| Albumin | 4.59 ± 0.27 | 4.61 ± 0.22 |
| T‐bilirubin | 0.89 ± 0.44 | 0.82 ± 0.25 |
No significant differences in any variable. BMI, Body mass index; HADS, Hospital Anxiety and Depression Scale; CIS, checklist individual strength; ALT, alanine aminotransferase; AST, aspartate aminotransferase; r‐GTP, gamma glutamyl transpeptidase; T‐bilirubin, total bilirubin. Data showed number (%) or average ± SD. *Pearson's Chi‐squared test. †Wilcoxon rank‐sum test. ‡Fisher's exact test.