Table I.
Baseline Characteristics
| Placebo (N = 20) | Romiplostim (n = 42) | Total (n = 62) | |
|---|---|---|---|
| Age (years), mean (SD) | 9.4 (4.7) | 9.7 (4.1) | 9.6 (4.3) |
| Sex, n (%) | |||
| Male | 9 (45) | 18 (42.9) | 27 (43.5) |
| Female | 11 (55) | 24 (57.1) | 35 (56.5) |
| Race, n (%) | |||
| Asian | 2 (10) | 3 (7.1) | 5 (8.1) |
| Black or African American | 2 (10) | 6 (14.3) | 8 (12.9) |
| Multiple | 0 (0) | 1 (2.4) | 1 (1.6) |
| Black or African American, White | 0 (0) | 1 (2.4) | 1 (1.6) |
| Native Hawaiian or other Pacific Islander | 0 (0) | 1 (2.4) | 1 (1.6) |
| Other | 1 (5) | 5 (11.9) | 6 (9.7) |
| White | 15 (75) | 26 (61.9) | 41 (66.1) |
| Baseline platelet count (109/l), mean (SD) | 19.9 (19.3) | 17.5 (10.7) | 18.3 (13.9) |
| Time since ITP diagnosisa (years), mean (SD) | 3.0 (2.3) | 3.0 (2.8) | 3.0 (2.6) |
| Splenectomized, n (%) | 1 (5.0) | 1 (2.4) | 2 (3.2) |
| Number of prior ITP treatments received, n (%) | |||
| 1 | 6 (30) | 8 (19.0) | 14 (22.6) |
| 2 | 3 (15) | 18 (42.9) | 21 (33.9) |
| 3 | 6 (30) | 8 (19.0) | 14 (22.6) |
| >3 | 5 (25) | 8 (19.0) | 13 (21.0) |
a
Years are calculated as (randomization date – ITP diagnosis/splenectomy date)/365.25. Partial dates of ITP diagnosis/splenectomy with missing day only are imputed at 15, partial dates with missing month and day are imputed as July 1.
SD, standard deviation; ITP, immune thrombocytopenia.