Table 2.

Overview of EME hyphenated to GC. EF and ER values indicated in italic are calculated based on data provided in the paper

Ref.	Tech.	Hyph.	Det.	Matrix	Compounds*	LOD	EF	ER	Vdonor	Vacceptor	ET	ST	EV
						(nM)		(%)	(ML)	(μL)	(min)	(min)	(V)
42	EME	offline	FID						2.1	7	20	5	200
				Plasma	imipramine, clopramine	1.7‐2.5	215‐250	72
				Urine		1.4‐2.4	240‐265	81
45	EME‐DLLME	offline	FID	Urine	quinoline, 2,4‐lutidine, 3‐methylpyridine, 4‐dimethylaminopyridine	1.9‐16	40‐202	1.7‐8.4	24	10	20	10	50
15	EME‐SPME	offline	FID	Plant tissue	2,4‐dichlorophenoxyacetic acid, 2‐methyl‐4‐chlorophenoxyacetic acid	2.3‐25	n.a.	0.6‐4.8	24	n.a.	20	12	50
16	EME‐SPME	offline	FID	Urine	doxepin, amitriptyline	3.6	n.a.	4.0‐10.4	24	n.a.	20	8	120
				Plasma	amitriptyline, doxepin	9.0‐18	n.a.	5.9‐3.1
44	Two‐phase EME	offline	FID	Academic	methadone, alfentanil, sufentanil	1.9‐3.6	353‐476	70.5‐95.2	3	6	20	12.5	80
16	EME‐SPME	offline	FID						24	n.a.	20	8	120
				Urine	doxepin, amitriptyline	3.6	n.a.	4.0‐10.4
				Plasma	amitriptyline, doxepin	9.0‐18	n.a.	5.9‐3.1
43	Two‐phase EME	offline	MS		imipramine, citaprolam, sertraline, desipramine				1.2	6	15	25	60
				Academic		0.36‐0.75	140‐175	70‐87
				Urine		n.r.	145	73
46	EME‐DLLME	offline	MS						24	10	14	10	240
				Urine	doxepin, amitriptyline, trimipramine	11‐51	753‐781	31.3‐32.5
				Plasma	trimipramine, doxepin, amitriptyline	10‐54	383‐397	16.0‐16.5

¹matrix is only mentioned when extraction performance is tested therein.

*in order of increasing LOD