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. 2016 Oct 20;6:35662. doi: 10.1038/srep35662

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) LDim (closed circles) decreased the amplitude of the daily rhythm in slow wave activity (SWA) compared to the baseline measurement (open circles). (b) LDim also strongly decreased the amplitude of 16–19 Hz activity compared to baseline. Data are expressed as percentage of the 24-h average at baseline. Registrations on day 0 and day 1 started at ZT12, but all data are plotted from ZT0 for convenience. Data are represented as mean ± SEM. If a significant main effect was detected, post hoc tests for differences from baseline were performed with student’s t-test and indicated by asterisks (P < 0.05) or double asterisks (P < 0.001).