Table 1. Effects of different concentrations of puerarin on action potential properties of rat ventricular myocytes.
| Group | RMP/mV | APA/mV | Vmax V/s | APD50/ms | APD90/ms |
|---|---|---|---|---|---|
| Control | −80.1 ± 2.7 | 112.5 ± 6.3 | 226.9 ± 12.4 | 71.8 ± 11.8 | 164.6 ± 21.4 |
| Puerarin (mM) | |||||
| 0.01 | −80.5 ± 2.2 | 109.8 ± 8.5 | 217.5 ± 10.7 | 86.9 ± 10.7* | 188.3 ± 11.5* |
| 0.1 | −80.3 ± 1.6 | 114.2 ± 4.9 | 242.1 ± 13.8 | 100.5 ± 14.1# | 221.6 ± 25.7# |
| 1 | −79.7 ± 1.5 | 115.9 ± 6.2 | 236.1 ± 15.9 | 123.6 ± 25.4# | 278.7 ± 28.2# |
| 10 | −75.3 ± 2.4# | 112.6 ± 4.7 | 238.4 ± 11.5 | 131.4 ± 19.6* | 330.1 ± 22.3* |
| 100 | −74.7 ± 2.6# | 113.8 ± 5.1 | 240.6 ± 12.1 | 146.9 ± 21.8# | 415.6 ± 28.4# |
| 200 | −73.5 ± 2.1# | 111.7 ± 5.6 | 237.8 ± 10.4 | 162.3 ± 23.5# | 439.5 ± 29.6# |
Note: RMP, resting membrane potential; APA, action potential amplitude; Vmax, maximal velocity of depolarization; APD50 and APD90, the APD at 50% and 90% repolarization. *P < 0.05, #P < 0.01 vs the control group, respectively.