[Table/Fig-7]:
Supporting evidence for the role of Msx and Pax gene.
I. Mimura S et al., 2016 [41] | Msx: Association between BMP in neural crest development. |
Feng X et al., 2013 [42] | Cell cycle regulation of dental mesenchymal cells. Inhibition of BMP-2 and BMP-4 expression during cap stage. |
Lin D et al., 2007 [37] | Expressed in mesenchyme, including the dental papilla; also in inner enamel epithelium. |
Tucker et al.,1998 [43] | Emphasis on relation between BMP-4 and Msx-1 in odontogenic mesenchyme. |
Thesleff I et al.,1996 [44] | Msx-1 and Msx-2 in the dental mesenchyme induced by BMP. |
II. Paixao-Cortes VR et al., 2015 [47] |
Pax: Present in embryogenesis as well as in adult organogenesis. Pax-9 important for odontogenesis. |
Hlouskova A et al., 2015 [48] | Pax-9 – transcription factor regulates mesenchymal odontogenic molecule expression. Mutation may cause tooth agenesis. |
Abu-Hussein M et al., 2015 [49] | Pax-9 mutation may lead to oligodontia or hypodontia |
Walton VT et al., 2014 [50] | Examined the co-existence between Msx and Pax gene in tooth agenesis. Assessed the importance of other genes in agenesis. |