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. 2016 Sep 1;10(9):ZE05–ZE09. doi: 10.7860/JCDR/2016/21719.8502

[Table/Fig-7]:

Supporting evidence for the role of Msx and Pax gene.

I. Mimura S et al., 2016 [41] Msx: Association between BMP in neural crest development.
Feng X et al., 2013 [42] Cell cycle regulation of dental mesenchymal cells. Inhibition of BMP-2 and BMP-4 expression during cap stage.
Lin D et al., 2007 [37] Expressed in mesenchyme, including the dental papilla; also in inner enamel epithelium.
Tucker et al.,1998 [43] Emphasis on relation between BMP-4 and Msx-1 in odontogenic mesenchyme.
Thesleff I et al.,1996 [44] Msx-1 and Msx-2 in the dental mesenchyme induced by BMP.
II. Paixao-Cortes VR et al., 2015 [47] Pax: Present in embryogenesis as well as in adult organogenesis.
Pax-9 important for odontogenesis.
Hlouskova A et al., 2015 [48] Pax-9 – transcription factor regulates mesenchymal odontogenic molecule expression. Mutation may cause tooth agenesis.
Abu-Hussein M et al., 2015 [49] Pax-9 mutation may lead to oligodontia or hypodontia
Walton VT et al., 2014 [50] Examined the co-existence between Msx and Pax gene in tooth agenesis. Assessed the importance of other genes in agenesis.