Table 1.
Demographic and clinical information of schizophrenia patients with complete or incomplete remission, and healthy controls
| Characteristics | Complete remission (n = 36) | Incomplete remission (n = 58) | Healthy controls (n = 55) | Statistics | P |
|---|---|---|---|---|---|
| Age (years) | 32.8 ± 6.2 | 34.0 ± 9.6 | 33.1 ± 9.8 | 0.249* | 0.780 |
| Sex (female/male) | 15/21 | 23/35 | 22/33 | 0.040† | 0.980 |
| Antipsychotic dosage (mg/d) (chlorpromazine equivalents) | 464.8 ± 310.5 | 461.0 ± 370.1 | - | −0.051‡ | 0.960 |
| Duration of illness (months) | 117.4 ± 80.0 | 126.7 ± 109.1 | - | 0.443‡ | 0.659 |
| PANSS | |||||
| Total | 48.6 ± 7.6 | 83.5 ± 16.7 | - | 11.731‡ | <0.001 |
| Positive score | 11.6 ± 3.9 | 20.5 ± 7.8 | - | 6.411‡ | <0.001 |
| Negative score | 12.9 ± 5.0 | 23.6 ± 7.0 | - | 7.994‡ | <0.001 |
| General score | 24.2 ± 3.8 | 39.4 ± 9.0 | - | 9.559‡ | <0.001 |
*F value; †χ2 value; ‡t value. Complete remission: These criteria comprise a severity criterion and a time criterion. With regard to the severity criterion, a score of mild (3) or less was required for all eight core symptoms of PANSS, including P1 delusions, P2 conceptual disorganization, P3 hallucinatory behavior, N1 blunted affect, N4 social withdrawal, N6 lack of spontaneity, G5 mannerisms/posturing, and G9 unusual thought concept. With regard to the time criterion, the symptom severity mentioned above must have been maintained for at least 6 months. Incomplete remission: These criteria comprise a severity criterion and a time criterion. With regard to the severity criterion, a score of (4) or more was required for all eight core symptoms of PANSS. -: Not applicable; PANSS: The Positive and Negative Syndrome Scale.