Fig. 4.

Intra-specific differences in amino acid biosynthesis, sugar transport and utilisation and natural competence. ORFs which contained a contig break are shaded in a lighter colour. a Intra-specific differences in amino acid biosynthesis. Each pathway requires multiple enzymes, as described by their KEGG module numbers. b Intra-specific differences in PTS components. Each sugar-specific system requires multiple subunits (typically IIA, IIB, IIC and occasionally IID). c Intra-specific differences in the genes involved in five-carbon sugar utilisation, as described in Fig. 6. d Intra-specific differences in the genes encoding natural competence proteins