Table 3.
Total mass removal rate, Mass adsorption rate, Sieving coefficient, and Plasma clearance of NGAL during CVVH
| T0 | T2 | T4 | T8 | T12 | |
|---|---|---|---|---|---|
| C i (ng/mL) | 879 (733, 1466) | 850 (685, 1525) | 859 (688, 1496) | 847 (689, 1417) | 844 (694, 1405) |
| C o (ng/mL) | 867 (697, 1451) | 845 (703, 1332) | 890 (661, 1416) | 834 (689, 1326) | 819 (646, 1415) |
| C uf (ng/mL) | 32.2 (26.7, 40.8) | 30.3 (23.6, 34.9) | 27.7 (24.1, 31.9) | 26.1 (21.2, 30.1) | 24.0 (20.1, 28.0) |
| M i (μg/min) | 107 (94, 183) | 104 (97, 194) | 105 (89, 197) | 105 (91, 182) | 110 (88, 180) |
| M o (μg/min) | 104 (92, 181) | 107 (88, 170) | 109 (85, 182) | 107 (89, 170) | 109 (85, 172) |
| M uf (ng/min) | 2189 (1330, 2748) | 1807 (1181, 3363) | 1888 (1309, 2312) | 2048 (1129, 3693) | 1397 (1018, 3471) |
| M tr (ng/min) | 1430 (239, 4914) | 1502 (−2500, 4801) | 3240 (593, 5544) | 3024 (−82, 5360) | 4620 (2540, 6687) |
| M ad (ng/min) | −313(−2576, 3470) | −1369 (−5611, −1682) | 1651 (−1494, 3308) | 354 (−2195, 3201) | 2216 (507, 5104) |
| SC | 0.21 (0.17, 0.26) | 0.19 (0.16, 0.22) | 0.17 (0.15, 0.21) | 0.16 (0.13, 0.20) | 0.16 (0.12, 0.18) |
| Clearance | 2.05 (0.39, 3.57) | 1.45 (−3.15, 4.28) | 3.74 (0.73, 6.09) | 3.56 (−0.45, 5.80) | 4.57 (1.85, 8.94) |
Data are presented as median (25th, 75th percentiles). CVVH continuous venovenous hemofiltration, NGAL neutrophil gelatinase-associated lipocalin, C i concentration in inlet plasma before addition of replacement fluid, C o concentration in outlet plasma, C uf concentration in the ultrafiltrate, M ad mass adsorption rate, M uf mass ultrafiltration rate, M i mass inlet rate, M o mass outlet rate, M tr mass removal rate, SC sieving coefficient