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Disorders in basement membrane integrity by prolonged dehydration. a An increase in BUN/sCr level in the dehydration group compared to the control group. b Dysregulation of basement membrane components at the transcript level. c The heatmap shows the signaling molecules related to cell-cell junction and cytoskeleton rearrangement underlying altered membrane integrity. Data are expressed as mean ± SEM. Student’s t test; *p < 0.05, **p < 0.01, ***p < 0.001 versus control group
